Inference Optimization

Techniques — quantization, caching, speculative decoding, sparse architectures — that cut the compute cost and latency of serving models.

Also known as: speculative decoding, quantization, Quantization-Aware Training (QAT), QAT, Post-Training Quantization (PTQ), KV cache reuse, Mixture of Experts (MoE), mixture-of-experts (MoE), MoE, time to first token, Multi-Token Prediction (MTP)

Knowledge Distillation (Teacher-Student Compression)System One / Non-Autoregressive Decision Models

How authors use it

Oldest first (extraction date when no publication date is known).

AuthorTheir termTheir meaning
DeepSeek v4, and the end of the OpenAI/Microsoft AGI clause
Simon Willison · 2026-04-30
Mixture of Experts (MoE)Architecture where only a subset of model parameters (the 'active' experts) are used per token — DeepSeek-V4-Pro has 1.6T total parameters but only 49B active; Flash has 284B total / 13B active. This is what enables their aggressive pricing.
Guest post: AI Inference Is Breaking Unit Economics
Turing Post · 2026-05-07
speculative decodingA technique where a smaller 'draft' model proposes candidate tokens and a larger model verifies them in batches, delivering 2-3x generation speedups
Guest post: AI Inference Is Breaking Unit Economics
Turing Post · 2026-05-07
KV cache reuseReusing the key-value cache from shared prompt prefixes across requests to avoid redundant computation, particularly effective for shared system prompts
Local AI
Mike Loukides and Claude · 2026-05-09
mixture-of-experts (MoE)An architecture where only a fraction of total parameters are activated per token, enabling large models to run on smaller hardware
Local AI
Mike Loukides and Claude · 2026-05-09
time to first tokenLatency before the model begins producing output — the key metric for interactive applications, where local models have a structural advantage (no network hop, no queuing)
Gemma 4 QAT models: Optimizing model compression for mobile and laptop efficiency
Omar Sanseviero (Google) · 2026-06-06
Quantization-Aware Training (QAT)A training procedure that simulates the effects of low-precision quantization during training so the model learns weights that survive compression with minimal quality loss.
Gemma 4 QAT models: Optimizing model compression for mobile and laptop efficiency
Omar Sanseviero (Google) · 2026-06-06
Post-Training Quantization (PTQ)Quantizing a model after training has finished. Treated as a baseline that 'often leads to performance degradation' and that QAT exceeds in quality.
Gemma 4 QAT models: Optimizing model compression for mobile and laptop efficiency
Omar Sanseviero (Google) · 2026-06-06
Multi-Token Prediction (MTP)A previously-shipped Gemma 4 inference acceleration technique; MTP QAT checkpoints are available so quantization doesn't lose the speedup.
Viability of local models for coding
Martin Fowler (martin@martinfowler.com) — memo by Birgitta Böckeler · 2026-07-07
QAT (Quantization-Aware Training)Quantization simulated during training (as opposed to applied after training) so as to better preserve model quality at a given compression level; mentioned as 'the newest buzz' but not yet personally tested by the author.
The Hidden Storage Tax on Every AI Conversation
HBR.org (Sponsor content from Solidigm) · 2026-07-20
time to first token (TTFT)The lag before a user sees any response, framed as being shaped by storage speed (retrieval, context loading, cache restoration) rather than GPU capacity alone.

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